Over the last month or two, I've been doing so much better- mentally. I don't know how long this will last, but I hope it lasts indefinitely- knock on wood! At one time or another I have been put on welbutrin, or lexapro, or cymbalta, and/or effexor (at various dosages) over the last couple of years... many times working up to max dosage... and they all have not been as effective for me as the Zoloft I was recently put on. I guess it is true that what works for someone may not unfortunately work for someone else. My Vet Center counselor kept harping on me to keep trying different meds 'till I find one that works. I just kept telling him there's really no hope for me... I'm stuck like this (misery) until I die. Around March I was started on 50mg/day for several days, then I was supposed to go to 100mg/day. I went to 100mg and got totally 'zombied' out, so I went back just 50mg. I was feeling better on the 50mg, but after about a month I started reverting back (having problems). Therefore, I took it upon myself to go up to the previous recommendation of 100mg/day. This time my mind/body tolerated the dose increase a lot better. By the next day I was doing better. No other medicine has made me feel this 'normal' again since coming back from the Iraq war in 2003. Lord knows, I've been wanting to be somewhat normal again for so long since. I've lost my career, my health, and a lot of other stuff that was important to me at one time- because of PTSD. Since initially being on Zoloft, I have only had about 7-14 bad consecutive days (moderate depression), and no bad days- since routinely taking 100mg(yet?). I feel like I'm starting to 'wake up' to life again. Although, my physical health is still enduring the repercussions from all the stress and neglect. The Zoloft has also curbed my appetite... I haven't lost any weight, but I am not 'bloated' like I used to be. The stubborn weight loss might be because of my diabetes. Since taking the Zoloft though, I have felt the motivation to take all my meds for my other health problems... something I have always had trouble with in the past as I hate taking medcine. I've also been taking a shower more often in contrast to only once every few weeks to a month. My sleep has also been a lot better. This Zoloft is the first SSRI I look forward to actually taking each day. I've been doing a lot of cleaning and organizing, did some lawn work, shot some of my airguns, chaperoned my daughter for a school field trip, road my bike a couple times, shaved my long beard (going to get first haircut in about a year), took my boat out (after many month's of neglect); I couldn't believe it still started! I was still somewhat nervous about being out in public, but not anywhere as bad as I was before... previously, I hardly ever left the walls of my house; not even to hang out in my backyard. The only exception was to run errands- if I wasn't already laid up at home. Recently, I caught up all of my Continuing Education Units (around 2 years behind) to fullfill requirements as a lab tech. I also started applying for lab jobs (the few available) and was even contacted to come in for an interview possibly next week. If I get this job and I'm able to keep it, that will be great. I hope I do not succumb to job stressors, and I'm able to tolerate others. I don't know how long all of this is going to last. Once I click on the 'submit' button below, my mind may go back to being 'dog shit'... or hopefully I may stay good for a year, several years, or even the rest of my life- who knows. March, April, and May are usually especially bad month's for me... I've been strong enough so far to not succumb to intrusive thoughts since being on the Zoloft. I'm getting tired now- I'm going to bed; such a far cry from the severe insomnia I have dealt with prior to the Zoloft. I just want my 'pre-Iraq war' health/life back.