A year ago I started to descrease my chemical medication use. I took diffent antidepressants for more than 16 years, and the last five years added sleeping pills and some other chemical medication with it. I weened myself off very slowly. Now after a year, I am on a small crumble of antidepressant. I cut the last pill into four sections and take one small crumble to go slow on the last part. I dont take anymore sleeping medication now for over six months, instead I use a high dosage of melatonine. It really helps me to fall a sleep. Now I am considering to switch over to a high dosage of st. Johnsworth, because I dont feel very well, and could use something that makes me more stable. I safely tried a low dosage of st johnsworth besides the little crumb of antidepressant. For now I feel the st Johnsworth is doing something but I am not quitte sure if it is helping or not. I have done some research and there seems to be a high dosaged st johnsworht ( 600 /900mg) out on the market. Ussually the dosage is somewhere between 245 and 300 mg. Yesterday I bought a sample of it, but I feel somewhat reluctant and scared to take it. When I doubled the amount of the cheap and regular St.Johnsworth, I was awake for the whole night, unable to sleep. I tried it twice to make sure it was from the effect of the St.Johnsworth, and not something else, that kept me awake. So, it is doing something, but I am not sure what, and if it will be safe enough for me to take it. Does anybody else have experienced effects of high dosed St. Johnsworth? Did it do something for you? I dont know if I am allowed to name the brand of the high dosaged St. Johnsworth.