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St. Johns Wort In High Dosage?

Discussion in 'Medications & Substances' started by sterre, Apr 2, 2012.

  1. sterre

    sterre VIP Member Premium Member

    A year ago I started to descrease my chemical medication use. I took diffent antidepressants for more than 16 years, and the last five years added sleeping pills and some other chemical medication with it.

    I weened myself off very slowly. Now after a year, I am on a small crumble of antidepressant. I cut the last pill into four sections and take one small crumble to go slow on the last part. I dont take anymore sleeping medication now for over six months, instead I use a high dosage of melatonine. It really helps me to fall a sleep.

    Now I am considering to switch over to a high dosage of st. Johnsworth, because I dont feel very well, and could use something that makes me more stable.

    I safely tried a low dosage of st johnsworth besides the little crumb of antidepressant.
    For now I feel the st Johnsworth is doing something but I am not quitte sure if it is helping or not.

    I have done some research and there seems to be a high dosaged st johnsworht ( 600 /900mg) out on the market. Ussually the dosage is somewhere between 245 and 300 mg. Yesterday I bought a sample of it, but I feel somewhat reluctant and scared to take it.

    When I doubled the amount of the cheap and regular St.Johnsworth, I was awake for the whole night, unable to sleep. I tried it twice to make sure it was from the effect of the St.Johnsworth, and not something else, that kept me awake.

    So, it is doing something, but I am not sure what, and if it will be safe enough for me to take it. Does anybody else have experienced effects of high dosed St. Johnsworth?
    Did it do something for you?

    I dont know if I am allowed to name the brand of the high dosaged St. Johnsworth.
    gizmo likes this.
  2. Anna

    Anna VIP Member

    I have never used it. I have heard it can help with depression, however it stops the contraceptive pill from working. So if you are using this as birth control you will need to use a barrier method like condoms to prevent pregnancy. Please be careful.
    gizmo and sterre like this.
  3. sterre

    sterre VIP Member Premium Member

    Thanks Anna!
    I am aware of the contraindication of using St. Johnsworth together with the pill. I dont use the pill or any other contraceptive.
  4. LoveIsHealing

    LoveIsHealing New Member

    I've tried St. Johns Wort, and never really felt much of a difference. I think it works for some people and not for others depending on which of your chemicals need a boost. Here are some other things that did help:

    Rhodiola
    Magnesium (glycinate)
    Colostrum

    Also, you can try a type of Folic Acid, it's called L-Methylfolate or Metafolin. They are using it to treat depression by prescription...I forget the brand name, but the prescription is a very high dose. You can buy 400 or 800 mcg. at a helthfood store and try that. :)
  5. AngelaMarie

    AngelaMarie One moment at a time is the best I can do! Premium Member

    Sterre,
    I am taking it now. I found it at an herb/vitamin store. They are 300 mg. tablets. I also noticed if I took them at night that I didn't sleep well. So, I take them in the morning. I don't notice anything right now like I did the first couple of days. You body gets used to it.

    Someone else on the forum warned me against taking an SSRI drug with the herb. It can react. So, I would wait until you have stopped that anti-depressant.

    I started with 1 capsule and then will double after a couple of weeks and see how that goes.

    From what I know it's like an anti-depressant and it takes a while to work. I figure I don't have anything to lose by trying it. I hate the drugs from the doctors. Nighthawlk started taking it the same time as me.

    Also if you drink it's not recommended with the herb.

    Good luck. If you have any questions or comments just contact me.:)
  6. sterre

    sterre VIP Member Premium Member

    Ah, nice that you and Nighthawk are trying Saint Johnsworth also!

    I dont drink ( I dont like the taste of alcohol), so I dont have to worry about that part.
    AngelaMarie likes this.
  7. sterre

    sterre VIP Member Premium Member

    Maybe it would be an idea to share our experiences in this topic?

    In this way we can compare our experience for the benefit of others?

    Yesterday I started with taking a pill of 6oomg ( wich contains 2 mg of hypericine), and today I took another one.

    Maybe it is a placebo effect, but I feel a bit more energetic today, than I felt for a long time.

    I also notice an increased craving for food?

    I slept really wel last night, but I took two melatonine tablets.
    AngelaMarie likes this.
  8. timetorecover

    timetorecover New Member

    I have never tried it but I am going to down the bottlE!
  9. Naya

    Naya New Member

    I have been taking St Johns Wort for several years. It helps immensely with my depression. My current primary care provider and my previous one (both MDs) are in favor of it, and have given me prescriptions for it so it is covered under my Health Savings Account. When I don't take it, I really notice a difference in my mood. Good luck with it!
    a3a2 and sterre like this.
  10. AngelaMarie

    AngelaMarie One moment at a time is the best I can do! Premium Member

    I think sharing is a good idea.

    Just be careful about taking so much so fast. I read you should start slow in case you have side effects. Just let me know.

    I am going to start taking melatonin in the next few days too. I tried valerian but I couldn't take it because of the smell. However, my cats love it.:)
    sterre likes this.
  11. sterre

    sterre VIP Member Premium Member

    So now you have really relaxed cats? How nice :)

    The St.Johnsworth is working just fine. I notice that it creates a mild shield to my current oversensitivity.
    I notice a difference, also the melatonine I take ( 2x 3 mg) is good for sleep.

    After 5 years on sleeping pills, I am so happy that the melatonine is working! After 16 years of AD's I am very happy that the ST.Johnsworth ( wich I was highly skeptical of) also seems to work in a mild way.

    How is the St.Johnsworth working for you AngelaMarie?
  12. AngelaMarie

    AngelaMarie One moment at a time is the best I can do! Premium Member

    I may be feeling a little better. I am going to give it a couple more weeks. Sometimes I forget to take it too.:confused: At least I don't have withdrawel symptoms when I do.

    I am super glad about the melatonin. I need to get some too. I am not too worried about it right now because I'm sleeping okay.
    sterre likes this.
  13. Belle

    Belle New Member

    Has anyone got an update to this? I am starting 450mg of St John's Wort to help with my anxiety levels and low mood as I have tried anti-depressants and they just don't work for me, side effects outweigh any benefits.
    I am also taking anti-histamines as dual purpose - to help with allergies and to have a calming effect.
  14. Lionheart777

    Lionheart777 Lion-hearted Survivor Premium Member

    I think that if you try St John's wort and it works for you then that is cool, but from what I have read it is only helpful in cases of mild depression. The reason is that, while it can increase serotonin levels, this chemical messenger cannot get across from one receptor to the next due it being re-absorbed by the initial receptor, thus the reason a lot of anti-depressants are selective serotonin re-uptake inhibitors (SSRI's). This allows the serotonin that is in the brain to circulate freely.

    You can use herbal medicine to build up the serotonin, but if it can't circulate through the brain, it just sits there and isn't helpful. Still, I say if you can't take anti-depressants then this may be a good alternative for you, but I have doubts of it's efficacy in cases of severe depression.

    Still, I wish you all success with it!!!

    Peace,
    Lion
  15. ellieggggg

    ellieggggg New Member

    The package says not to take it if you have a peanut allergy even though there aren't any in the ingredients, so I'm guessing it was made in a nut environment - has anyone experienced any allergic reactions?
  16. Hashi

    Hashi VIP Member

    I found St John's Wort didn't help with depression, and made me feel worse because of the side effects - tiredness, stomach upset, increased sensitivity to things I have an intolerance to. That may be why it's not recommended for those with a peanut allergy - it can make other intolerances worse. I have no idea how, but this happened with me.

    I sympathise very much with wanting to find an alternative to antidepressants, and I'm glad for those who find St John's Wort helpful. I hope that anyone posting here who's trying it falls into that category, and it helps.

    Please be aware, though, that it can have side effects, and can interact with other medicines or herbal remedies. So go carefully with it, and always check if you're taking anything else (even "natural" remedies) whether there might be an interaction. There's some good information here:
    http://www.mind.org.uk/help/medical_and_alternative_care/st_johns_wort_hypericum_perforatum
    (although if you're taking anything else, I think you need to check with a practitioner about interactions, rather than just google it).
    Dissociation likes this.
  17. Elizabeth-Ann

    Elizabeth-Ann New Member

    I take 500mg morning and 500mg evening. In our country it is quite common and accepted. I have good experience with homeopathy too. Especially for sleeping and nightmares.

    I am taking citalopram although, but it does not cause addiction nor other negative things, but I do not take other medication for the moment, even if I am a diagnosed severe case of CPTSD, going slowly on the path of healing... :)
  18. vikingr12

    vikingr12 New Member

    I have had PTSD and all the accompanying feelings for many years, delayed and suppressed. St. John's Wort for me works best in the morning 900 mg along with Sam/e on an empty stomach (with water of course). It works very well for me but lasts until the afternoon. I am thinking of taking another one then.
    SAM/e and GABA do well for mood and anxiety. And melatonin and tryptophan at night really do help me sleep. I do have to take Ativan twice a day at times.
    Am I cured? By no means. I will be seeing a therapist for some time -- again.
  19. LizardViolet

    LizardViolet Active Member

    I have suffered from depression since my teen years and I find that St. John's Wort is helpful. I've been taking it for quite a few years now. I take one at lunch and one at dinner; my depression is linked to PMS so I take just one a day for the week or so after my period, then go back to two. I also take a B complex and magnesium. I increase the magnesium when I increase the St. John's Wort. I also take GLA (you can get it as fish oil, or evening primrose oil, or flax and borage oil), which also can have some positive effects on mild depression. I tried an antidepressant many years ago and found that it was like hitting my system with a sledgehammer. The St. John's Wort is much more gentle and subtle.
  20. Belle

    Belle New Member

    Well I tried it and I think it worked a bit but not enough to help me to feel ok, now taking meds from GP.
  21. Dissociation

    Dissociation Well-Known Member

    I find St. John's Wort definitively helpful for light-moderate depression, maybe it doesn't work for major depression. And I don't think it will work after a long period taking chemical strong antidepressants.

    Antidepressants don't work for sleeping. If you sleep better when you are medicated for depression it is because insomnia is one of the symptoms of depression.

    I take 370 mg., that correspond to 1 mg. of active ingredient in the brand I use.

    :geek:
  22. Artemis

    Artemis New Member

    I take Remotiv. It is important to pay for a good quality St John's, as the cheaper products generally dont work (I think that is the major reason for why some people find St John's ineffective). Most clinical trials used dosages equilavent to approx 5mg dried herb per day (see "A Clinical Guide to blending LIquid Herbs - Kerry Bone), most available tablets out there have much lower dosages.

    I'm taking St Johns and have been combining it with many other serotonin enhancing agents (melatonin, 5HTP, SSRI's etc) and have not suffered with Serotonin syndrome yet. I think you would have to overdose or be highly sensitive to have any problems. My psychiatrist also knows I'm taking St Johns and she has no concerns about me using antidepressants and sleeping agents in combination with it.
  23. intothelight

    intothelight Totally Quackers Duck Staff Member Premium Member

    Just a note of caution. Even though supplements and natural herbal remedies are helpful, it is critical to run these by your pharmacist if you are taking other types of medication.

    It is surprising the adverse drug reactions that can occur and also some benefits/effectiveness of drugs can be reduced or negated.
    BloomInWinter, Hashi and amethist like this.
  24. Hashi

    Hashi VIP Member

    When you say she has no concerns, that is presumably based on her knowledge of you and her general monitoring of your medications. (If not, I'd be alarmed!)

    As patients, we need to always check. There are a number of medications on the list for possible interactions with St John's Wort, including oral contraceptives as well as SSRI anti-depressants and others. We have no way of judging how likely we'd be to experience a negative interaction.
    BloomInWinter likes this.

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