Hi, I have C-PTSD & I am also into holistic health. I was taking my supplements faithfully but over a period of a few months I started to feel very badly w/ so many symptoms that I was not feeling before! There was quite a list of them which came to about 25 symptoms! It was really scary & I cried & asked the Lord to help me find the answer & it became clear to me that I cannot stop taking my adrenal cortex supplement! Usually professionals do not address the importance of taking care of your adrenal glands & how they ar weak, depleted, fatigued from the stresses of life PTSD. I hope this will help someone. There's plenty to check out online about it. Also, Dr. Wright's Tahoma Clinic has some good articles re: the adrenals & taking lithium orotate (not a prescription) to help us.