While abnormalities in the adrenergic and noradrenergic systems, both integral in the fight-or-flight response, are thought to play a role in the development of post-traumatic stress disorder, until now there has been no genetic evidence of this connection. A recent study has found an interaction between the ADRB2 gene and childhood adversity. For individuals with two or more experiences of childhood trauma, such as abuse, genotype was associated with risk for adult PTSD symptoms.
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