Drugging yourself up to escape means developing all the new problems that come with that, like increasing depression and anxiety, and is likely to continue to fuel your despair and desire to escape again, and not to face the really difficult and real problems in life like you want to be able to do.
Using meds like you are and seeking to use more powerful things is likely to be chemically fueling your depression, and sense of despair, not helping it. Same with anxiety.
Your therapist actually doesn't seem to understand radical acceptance and nor do you. Radical acceptance is not giving up and not changing anything in life. I used to think that's what radical acceptance was and I balked at it as well. Just "accepting" things as they are and doing nothing about them is learned helplessness.
Check out the book, "Wherever You Go, There You Are." My therapist gave this to me and it dramatically changed my understanding of radical acceptance. It became a tool that helped me work for change in my life much more effectively.
It also became a lot easier to change things at work and elsewhere as I processed the trauma through emdr and somatic experiencing, and less on trying to fix all the circumstances of my life.
Your therapists advice was crappy, and it makes a lot of sense why you wanted to escape. Her advice was one of escaping and running from problems rather than working on the riot issues behind them. In the end, all the problems will come back, and usually worse.
I'm really glad you have emailed new therapists and suggest you think of looking for one that works with addiction, even if you don't have a full blown addiction. I have found that trauma therapists with some experience with addiction tend to have a lot of understanding about the pull to escape problems, to run from them, and how much that doesn't work (like divorcing your wife and moving away) and how to instead face them in ways that are not overwhelming but actually doable.