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Endromax

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Koala

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So a new one was prescribed today...

I have been on so far.
120mg Cymbalta / 30mg Avanza
120mg Cymbalta / 60mg Avanza
Brintellix
Valdoxin

So now trying endromax, anybody have any experience with this drug?
I start tomorrow morning but just doing some research..
 
Ah.... Do you have a chemical name for it? Because if it's Alendronate Sodium / Fosamax brand name over here, that's an Osteoporosis medication. Not finding any evidence in a cursory search it's ever been used off-label for any kind of mental health condition. In fact, there are no cognitive-emotional side effects listed whatsoever, and the only neurological side effects listed are dizziness & vertigo. ((One way to cheat-look at what a med may be used for off-label is to look at the side effects list.))
 
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Every time a doc prescribes a new med, or any med for that matter, I do some dd like you are. Sometimes I flat out reject them because the side effects are worse than the symptom. But that's just me.
 
I hear you loud and clear woodman.. sad thing I know what works for me but we are not allowed to have it as it is a dangerous drug with 2 - 5 side effects... whereas what the doc describes me only has 20 - 30 odd side effects.. go figure.. stupid f*n government.

Friday, that medical name is reboxetine..
Not normally used for depression but I keep rejecting their stupid drugs, if I make a mistake at work it can effect 30k people and they keep giving me stuff that makes my mind numb and stops me concentrating and therefore has the potential for me to loose my job.. but hey it is all a big joke to them, so lets keep being their guinea pigs and smile..
 
Ah... That makes a helluva lot more sense! Endromax kept popping as the A.Sulfate in my PDR. But it looks like just a typo. Reboxetine has a brand name Edronax.

Short answer, not that one.

Long answer; But I have taken another short acting Selective Norepinephrine Reuptake Inhibitor... Atomoxetine/ Strattera. It's an ADHD drug. Didn't do much for ADHD (I'm comorbid, but more to the point, I react weird to meds *because* of my ADHD, and it worked just fine with it), but it did a whole helluva lot for my PTSD stuff at very, very low doses. In theory an adult dose is 80-160, child dose is 40-80. I only took 10. ((I started low, worked up to 160, then backed off until I was at the level that felt best... Which is standard protocol for ADHD meds.))

One of the things I loved about atomoxetine is that it had a wicked short active life. About an hour to work, and half life of 5 hours. Out of your system in 24 hours.

Looks like Reboxetine is about double... 2 hours to work, 13 hour half life, 3 days still in your system. Which means it's still short acting. Most antidepressants have half lives of 2-5 weeks. Means a helluva taper & withdrawal.

There's a little bit of talk (very little) of using Straterra/Atomox for PTSD. It's already used off-label for anorexia. Selective NorEpi's aren't used much, in part because their effects tend to be subtle... Rather than boom! like serotonin re uptake inhibitors. But anecdotally, part of why it tends to work well for ADHD & Anorexia is that it gives a level of control over your own thoughts and emotions. It doesn't alter your thoughts or emotions like a lot of drugs, but instead let's you choose your own. Thought pops up? Nope. Not dealing with that right now. Crushing shame? Nope. Let's move past that for now. And everything is saved for later processing. You can still deal with stuff, just on your own timeframe. Which is crazy useful. Also mad calms the hyper vigilance & intrusive thoughts... Whether it's from the constant influx of info around you (ADHD) or about your own body (anorexia)... And in my case gave me full stop *control* over my anxiety, flashbacks, and insomnia.

If rebox works anything like atomox? I can see why it would be shit for stand alone depression. Depression is pretty damn global. But I already had a leash on my other problems. Atomox meant I wasn't fighting for control of that leash. LOL. Like I had a well trained dog at the end of it, instead of TheBeast.

So, personally, I would be cautiously optimistic.

But I'm always cautious with meds. None of our neurochem is the same. What works one way in one brain, will not work the same way in another.
 
As far as being guniea pigs? Neurology is a baby science. We don't have a way to predict how any brain is going to respond to any medication. Period. All we have are trends. The only way to find out how your brain is going to respond is by being Alice. Eat Me / Drink Me... And then paying f*cking close attention to what happens. Positive, neutral, negative.

If you have a very good doc, they can look at your personal trends, and start mapping the motherf*ckers out. But to get those personal trends? You have to take shit and see what happens. There's simply no other way to find out. And, quite frankly, good docs are rare. Really, really rare.

I'm lucky... Because I'm ADHD, I already know how I'm going to respond to a helluva lot of meds. Stimulants will be calming, mood stabilizers will f*ck me sideways, & antipsychotics will make me psychotic. Antidepressants are a mixed bag I'm not willing to play with, because they take so damn long to work & Ive had bad reactions to short acting meds that nearly did me in. If I can barely hang on for 24 hours? No way in hell am I going to test myself for 2 months. Best case scenario I'm the only one who dies if things go bad. Worst case? I've been f*cking nuts before. Not going there again. 24 hours I can writhe through. I don't trust myself past that. Other people are stronger than me. Mad respect.

But even just taking the one class (stimulants) that are generally calming? About 75% I cannot effing take. Ugh. Gross. I hate them. Side effect are unsat. Every stimulant has a different "flavor". Some kill my personality. Nope. Some drop kick me into rage. Um. Bad idea. Some make me love everyone. Gross. So even knowing a class works generally one way? There's still a helluva lot of trial and error. Literally.

Baby Science.
 
Awesome, thanks Friday.. very much appreciated..
Have been struggling fighting this ptsd thing for 15 years now.. Always learning new things.

Yep took me many months to get off Cymbalta and Avanza with throwing up and etc.. so glad this is short acting and short half life.. :)
 
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