I took zoloft on two seperate occasions. The first I was on it when I was sexually assaulted. I don't want to scare anyone, because I don't know for sure that it had anything to do with me letting my guard down and making such a mistake by going with this person...but the fact is I was on AD's when I was assaulted. I have told myself that maybe that caused my judgement to not be so sharp that night...which helped me to deal with it more.
Purely chemically though, zoloft did make me feel more normal again, though I decided after 3 weeks that I no longer needed it and didn't want to be on them...I never wanted to be on them, I'm extremely cynical about the pharmaceutical companies and the way that doctors hand out diagnosises for every little thing these days, and the deal between doctors and pharmaceutical companies...but hey, I needed help, and I'd gone without for about 9 years before I finally succumbed. Could have saved myself a lot of grief if I'd just gone on them when I first started getting dperessed and was traumatised.
I guess the effects of any drug will be different with every individual. I found zoloft to be great both times...though, if you do decide to ween off them, do it the intelligent way...ween off slowly and with your doctors supervision. I just stopped the first time, and it caused A LOT of trouble for me. I ended up homeless because I schized out so badly I nearly kicked my mother in the stomach and my father pinned me down and hit me (after I'd been sexually assaulted mind you) and then kicked me out...I ended up in a DV shelter for 6 weeks. So yeah...do it the smart way. Once the drugs are in your brain it's unwise to just deprive them of what they get used to having...and until you can naturally provide these chems again, it's best to just let them do their thing until you feel more able to deal with life without them.