I have severe side effects to the majorty of drugs I try.
@Nighthawk I can relate all to well to his, and some meds make things so much worse. At one point I told my doctor I didn't want to try another anxiety medicine. I'm told I'm very sensitive to medicine.
Then some major triggers - I went so far downhill. I was told I have "extreme anxiety", and that higher doses can make extreme anxiety much worse. Started 12.5mg of Zoloft and it started helping in less than a week. Suppose to go up to 25mg after week or two. (also, on a benzod in afternoon and night for now.)
Also, has your doctor talked to you about GeneSigh genetic testing to find the right one? It helps direct your doctor to medicines based on the way your body metabolizes medicine - also those to avoid if possible.