Yep. Mine is trained to ignore my cat, random bunnies that run by, squirrels, etc. I love my cat very dearly, and I was hesitant to have a service dog myself. Even if the dog can ignore the cat, not all cats can handle a dog even being in the room. However, if you get an already trained service dog, or introduce one as a puppy, then it has a greater likelihood of working out. My cat now occasionally hisses at the dog, but the dog listens and goes away. She knows who is boss. My cat also occasionally curls up and sleeps on top of the dog. They seem to have worked out a working relationship. :)