Whenever I start taking a new medicine, I purposely stay with someone who knows I am taking it for the first time, and tell them to watch me closely. I stay with them for both the first and the second time I take it. (My neighbors were kind enough to watch me the last time I had to do this and a close friend did so the time before that). I instruct them to call 911 if for any reason I start to act very strangely or have some physical complaint, pass out or whatever. As to side effects that take longer to develop, these usually are not life threatening and you can monitor them yourself. If you don't like what develops, talk to your Dr. and get something else prescribed.