I thought it might be useful to bring this thread back up since some may find themselves considering these meds. I found this thread because my med nurse put me on Abilify nearly two weeks ago. I'm also on Lamictal (in addition to Remeron and Prozac daily, and clonazepam as needed). It's a lot of medication, but I feel I'm functioning better than I was before them. Well, maybe I'm not functioning a lot better, but I'm more accepting of my limitations, don't beat myself up as much, and am finding it easier to learn to better control my rages.
In spite of my hard work on self-talk, getting myself motivated, and pushing myself (and working on learning when to push myself and when not to do that too much) - the Remeron and Prozac weren't doing much more than helping me get to sleep at night. I remained very depressed and frustrated even though I worked so hard at getting better and resolving my traumas.
He then added Lamictal, which he described as an anti-convulsive that has been shown to be helpful in treating depression and mood stabilization - that's why it's sometimes prescribed for people with PTSD. My husband and I noticed an almost immediate improvement in my mood and I haven't noticed any side effects.
After a couple months, though, the improvement from the Lamictal lessened considerably and he started wanting to put me on Abilify. My depression symptoms and rages began taking over my life again even though I was working on my issues in therapy. He described Abilify, as others have noted, as an anti-psychotic that also had been shown to help depression, hence why it's prescribed for PTSD. So I finally decided to give it a go. My primary reservation about Abilify is that it can increase your risk for diabetes, which I've been genetically at risk for all my life. So I have to get a prescription for test strips (which are wicked expensive) to keep better tabs on my blood sugar. After a lifetime of being borderline, I can usually tell when it's low or high and have kept it under pretty good control, but I don't want to take the chance of not being more aware. So far the only side effect I've noticed from the Abilify is a much decreased tolerance for heat/intense sunlight. I don't know if I'll stay on it. I'll probably give it another two weeks or so while keeping close, objective tabs on my blood sugar, then do another cost/benefit analysis with my nurse.