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Immediate Relief- Is This Placebo?

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Last night, I took Prazosin for the first time, right before bed. Other than feeling a little dizzy and nauseated, I actually felt a little better, somehow. Calmer, maybe? It still took me a long time to fall asleep despite exhaustion, so no change there. Is this just a placebo effect? I'd think after my experiences with meds (you name it, it was probably forced on me before I was 18 b/c my mother was a powerful and manipulative woman who convinced shrinks that I needed to be controlled.

When they'd start to get suspicious, she'd say they weren't any good and we'd go see a new one.) that I might be relatively immune to placebo effects. I'm pretty jaded and really hate the fact that I cannot seem to function without my Lexapro. SSRIs have been my constant, if sometimes unwelcome, companion for over a decade now. So how is it that this morning, even though all of my physical problems persist, I feel not quite as horrible? I actually got up when my husband left for work (first time in days I'd managed that) and didn't feel the urge to cover my cereal in obscene amounts of sugar in a desperate attempt to feel better.

It's like I've been begrudging having to get out of bed nearly every day for years now, and I didn't feel that way today. It can't be just that we finally had a sunny day yesterday, since it was sunny in August when I thought I couldn't go on. Has anyone ever heard of Prazosin providing an immediate reduction in nightmares? I don't remember a whole lot about my dreams last night, and I don't think they were good, exactly, but they were not the terrors I often have. It has taken me a while to figure out how to describe this feeling.

I feel...somewhat....rested....(?!) Like I actually SLEPT! Don't get me wrong, I still feel very sleepy and could easily go back to bed, but I don't feel like it's an overwhelming, oppressive urge that cannot be denied. My head still hurts, and the muscle aches that can sometimes be unbearable are still there, although currently at a fairly tolerable level. Something is different, and I am so jaded, so tired of putting my hope in things, esp. things that promise me relief, that I am trying to approach this skeptically. But other than yesterday being sunny, I cannot think of anything that could have had even a small positive effect.

I realize that even if this drug's effect is for real (i.e. not me just imagining), that the long road is far from over, but I'm just scared to trust that this rug of hope for healing could be pulled out from under me. If it makes a difference, my shrink feels I have a genetic hypersensitivity to meds, esp. those that affect the autonomic nervous system, and esp. the sympathetic branch (that's the fight-or-flight one), so he actually instructed me to open the capsule, stir the powder into juice, and drink only half the juice before bed.

As it was, I felt a little woozy after about 20 min, not as bad as the time I passed out after donating blood, but similar to that feeling. So maybe it's not totally impossible for the drug to have had its intended effect, too? I have always responded to some chemicals rather strongly-- I love the taste of coffee but try to avoid the regular kind at all costs (and decaf, too, since I have IBS).

I can't even have epinephrine when I go to the dentist for a filling b/c my heart goes nuts if they forget and give me the novacaine with the epi in it. I've always been this way, although maybe the PTSD has something to do with it, too? Anyway, sorry to ramble. I just wonder if anybody else has felt immediate postive effects from Prazosin or heard of anyone who has.
 
Prazosin has worked immediately for me from the first time taking it. (...and I am still taking it). So I wouldn't be surprised if it the medicine is doing its job rather than your getting a placebo effect.

I really Luv this medication as I haven't had a nightmare/night terror since beginning this regimen. Still, I have to say that everyone responds differently to medications and so you may want to give it a little more time before you make up your mind about it.

good luck,
LH
 
Thanks, Lionheart! Oh, and to clarify, in case anyone was wondering/confused/concerned, many dentists do keep novacaine without any epi in it on hand. Thankfully, it seems to do the trick for me just fine when I have to get a filling. Didn't want anyone to think some dentist was actually doing his work without numbing the person's mouth first! Yeah, that would not be so good. Makes you glad for novacaine, huh? lol.
 
I am sorry falconscape,

I have only said that it has worked for me and what my experience is with this medicine... *stops scratches head... umm...It would be wrong of me to say as I am not a doctor or even a nurse. :(

I found a link, but I cannot say if it empirical evidence one way or the other and I would not want to misguide you in any way. :tup: I was only describing my experience with the medicine... umm..

My best thinking tells me to suggest you ask a licensed psychiatrist as it is my understanding that they are the ones trained to make that assessment, (at least in the US where I live).

please forgive me if I have misrepresented myself,

Lionheart
 
That's great. I'm seeing my psychiatrist in 2 weeks. We'll certainly be talking about this! I'm getting tired of breaking things on the nighttable, kicking myself out of bed, and hurting my hands, feet, etc.
Thanks.
 
Hi I am new here, but this thread seems intresting to me.

I have nightmares nightly, night terrors and the worst experiences ever with sleep paralysis if you know what that is, I think it's prettty rare anyway. I kick, punch all kinds of crazy stuff in my sleep, is this a drug that could be of use?

I have had hard times explaining these actions to women who have been there for this, thank god I didn't hurt them but I am worried I may.

<Edited for grammar and paragraph breaks inserted>
 
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