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Depakote Er For Ptsd???

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Nylen22

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HI,

I was recently put on 750 mg of Depakote ER. I have looked far and wide on the internet and have found only a little info about this drug being used for PTSD. I know it is mainly used for seizures and bipolar (which I do not have). I was curious if anyone else has taken Depakote ER for PTSD? If so, did it help alleviate symptoms? How long did it take to start working? Really anything about the experience you could think of would be helpful!!!!

The Doc also put me on 100 mg of Seroquel for sleep. It no doubt has helped me sleep but I feel pretty out of it all day (however, only my 4th day taking it). This also confuses me because both drugs are essentially for bipolar disorder? I don't know, I have had bad experiences with meds before and I have a hard time trusting pdocs. I feel like they are essentially experimenting! :(
 
Im not a Dr. and I dont grasp the entire situation but seriously... DEEP BREATH
First thought to mind... Shame on your DR. Question everything they try to throw at you. I got committed once (under wrong pretense of suicide) and first thing they wanna put me on is depakote I knew enough to say no and refuse, after daily intimidation from this DR and many others PCDOCS, Neurologist's, and physcs have tried this same bullshit. Making threats of taking me of my benzos, no taper, or no release till I take it. Went to court over that almost, DR backed down finally. Lots of threats of that nature to get me to take it.
Shit I have partial/complex seizures and I would rather endure those than take depakote, From all my research from books to literally interrogating people about there medicine 50+ from kids to grown men and woman who have been prescribed aforementioned drug for off-label uses bipolar and very few on it alone for seizures(mainly bipolar) really dont undserstand how bad this drug is for them or the possible side affects and their very real long-term effects.
Dr.'s just love to prescribe this drug for some reason $$$ script pads do make them a great deal of money after all...

As for experience with depakote I only took it for 2 weeks but god damn, I felt like my personality was breaking, I felt very dulled out. Reminded me of SSRI's(SNRIS) Like I cant tell where my base personality is or feelings stem from me or which parts are from the drug. Everything is kinda groggy, as if your constantly in a state of just awaking after very little sleep. It also gave me facial tics but I have tremors to begin with. I felt impaired for sure, just kinda dazed. Terrible terrible terrible. It scares me how many kids are taking this crap unquestionably for off label uses but I’m off-point.

Now seraqaol I would say is one of the major Dope em so they don't feel. I would never take this under any circumstances. They give this to rowdy inmates in prisons and hospitals. Literally the most common "zombie drug" pushed in this day and age. It's an anti-psychotic that messes with a lot of different receptor sites. From Histamine H1 H2 to Setatoinin sites to Dopamine sites. Also the lower the dose the more Sedating, the higher the dose 100 -200 "mood stabilizing effects" really just being blunted... and higher than that for anti-psychotic effects around 400-600MG 25MG would knock you out way harder than 300 would because the h1/h2 receptors must be flooded for your brain to send it to the other neurotransmitters.
Seriously this shit is poison... I would put it so " A chemical lobotomy for pesky patients" It was made for schizophrenia to calm them and reduce delusions. Hell my grandfather was just put on this in the hospital to basically keep him from causing the nurse staff problems. I would never take Quetiapine for sleep. Its just a sloppy ass drug.
Not even as a last resort... antihistamines (Promethizine, Hydroxzine)come to mind as some of the better ones. Would have the same effect as that dose of Quetiapine while binding to a lot less receptor sites. After all it only makes you sleepy because of its effects of the H1/H2 receptors. Less side effects.

I hope this helps cuz' honestly for pstd I think this would only make things worse unless numbness is the goal but I don't understand the entire situation or medical history so excuse me for being blunt about all this. Thats a lot of Valporate for a starter dose too. PM me if you'd like to.

<Signature removed from all posts: Forum rule 11>
 
Candy Champ,

I really appreciate your message! Clearly the message took a lot of time and effort and many strong emotions (which I understand, I have many strong emotions that go hand in hand with PTSD treatment and professionals acting voluntarily or involuntarily incompetent). I did find a few studies that were done in the mid 2000s that came to the conclusion that depakote does not reduce the symptoms of PTSD and in some cases made PTSD symptoms worse than the placebo. As far as the Depakote goes for myself I think I am going to start taking myself off of it tonight. I have been taking 750 mg (3 pills), but tonight I am going to take 500 mg (2 pills). I have never liked taking medication, and up until this point I had gone a long time without taking any, but I have had issues in the past with doctors starting me out on too high of a dose and giving things to me as a teenager that were dangerous.

As for the rest of the post, is there anyone out there who has been on Depakote for PTSD? Did it do anything positive???
 
You might have developed obsessive behaviors, social perhaps? The drug can also give you that slight moment of thought before you speak, giving you a chance to think twice before saying or doing.... It would be interesting if a doctor prescribed that to you for something like that. But it is common to develop obsessive compulsive tendencies as a result of coping with ptsd.
 
Those are pretty powerful medications. I'm not a professional by any stretch and over this past 10 plus years since my meltdown I've had many drs push a lot of meds on me, Seroquel and Depakoe are just some of them. I question everything now and look EVERYTHING up, especially side effects and other people's reactions to said medications as some of the bad effects are not necessarily listed, I found this out on my own.

I'm not saying that there aren't times when medications are useful because personally I do believe they are. I was in a psychotic state and at serious risk to myself, I hadn't slept in literally weeks and it didn't look like I was going to. I needed intervention and more than just locking me up and trying to talk to me because there was no talking to me. Of course everyone is different.

My experience with medications has been a love/hate, after several years I have found that having finally found therapists to work with I have been able to cut out all but a couple to do with my complex trauma.

Good luck,
Peace,
Rain
 
I was on depakote. It is a mood stabalizer. It didn't work for me, but everyone is different. I was put on it because one of mis-diagnosis was bi-polar. I didn't know that they used it for PTSD.

I take seroquel now. They put me on 200mg and I was completely out of it. Now I take 12.5 to 32.5 per day. I still feel a little out of it sometimes even with that low dose. If you look up seroquel you will see that being sleepy is a side affect and it isn't really suppose to be prescribed for sleep, but the doctors do it all the time. Just be careful because seroquel is almost impossible to come completely off of once you are taking it. I have heard that from others too. I have tried to go completely off but the side effects are horrible!!

I wish you luck!
 
I take Seroquel (Quetiapine). I am currently on 50mg at night. Was previously taking 25 mg in the morning as well. I have found it a wonderful drug. It really helps with the anxiety and helps me to sleep. I have been taking it for over 2 years now.
 
First of all thank you for your responses...

gamereign555:
It is possible that the doctor placed me on Depakote for that very reason. I stopped sleeping this past August because of some events that triggered me. Over the past ten years I have become very aware that sleep = many few PTSD symptoms. As the weeks went on getting 4-6 hours of sleep (I know for some of us that is a lot, but for me I need 7.5-10 hours to function) I began to slide. I tried everything from exercise, to progressive muscle relaxation 3 times a day, to eating perfectly, to trying 5-HTP and also Melatonin, I listened to white noise, I listened to sleep hypnosis tapes, in my opinion I tried nearly everything and it just got worse and worse. Sleep became something that I obsessed over all the time, I felt that without sleep my life was in trouble. By about mid November my life was a mess. Issues with my girlfriend began to escalate. I was having major problems with intrusive thoughts, major problems with trust (in an obsessive way), major problems regulating my emotions, major problems feeling numb (well feeling anger, but not love), acting more impulsive, and more and more depressed each day (feeling like I was not in control). I became very controling to the people around me, not because I wanted to be mean or let them get on with their own lives, but because I was terrified and I wanted them to stop triggering me (and pretty much everything that people did triggered me). I became very obsessive, very keyed up in everything I did. So possibly that is why I was given the Depakote??? I am only 8 days into taking it, but it does seem that my obsessive behavior has decreased slightly.

As for the Seroquel if nothing else I have been sleeping. I hadn't slept 8 hours since about mid August and since Wednesday I have slept between 9-10 hours each night. I do feel that this is important for making up the massive sleep debt that has accumulated. I am hopefully that if I continue to sleep this way for at least the next few weeks that in its own right will make me feel much better.

Srain:

I do understand what you are talking about with checking up on the medications. When I first developed PTSD I was 19 years old (10 years ago). I knew something was majorly wrong with me, didn't have a clue at the time what it was. I was attending Oregon State University and I went to the Health Center and they gave me Paxil (started me out on way too high of a dose, plus I was a teenager). I started seeing things, hearing buzzing noises, and I felt like I could be homicidal (to say the least my first experience with a drug for the brain was not a pleasant one). I ended up being hospitalized.

Over the years I have been on Paxil, Celexa, Effector, Zoloft, and Wellbutrin. Some of them helping in some ways (I think taking away some of my depression and some of my obsessive compulsive tendencies), while in other ways making me much worse.

I have been completely free of medication for two years until this past week. The funny thing is that besides the past few months it was the best period of time in my PTSD life that I have experienced. This past week I checked myself into the hospital because I had tried all of the coping techniques I have learned over the years and I kept sliding down the slope, I just couldn't stabilize myself. I hate drugs, but I realized that every time in the past that I began to slip I was put on some SSRI or something else that helped me pull through. I saw that if I didn't get help now that I might not be around in the next 4 to 5 months (I felt like I was losing my mind). :(

I am aware of the crappy side effects of the two drugs. :( I am looking for a new phys doctor, the guy who prescribed me the medication works in the mental health ward of the hospital I checked myself into, so I need to find a follow up appointment. I am attempting to find a doctor who has a background treating PTSD and trauma disorders, but unfortunately I lost my job because of my breakdown and northern Nevada in general has fairly crappy mental health. I just have to keep trying to do my best!

AngelaMarie:

Also thank you for your post. Yes, Depakote is manly used for seizures and bi-polar disorder. I did finally find a few studies that indicate it can be helpful to some people with PTSD. As for me it is still way to early on and we will have to wait and see.

The Seroquel really knocked me out the first few days, but the last couple I feel much better and much more awake in the day time. A big problem is that the stuff costs me $200 even with my insurance. That really sucks... and at that rate I will not be able to afford it very much longer. As for crappy withdrawal, that is one of my least favorite experiences in the world. A few years ago when I just graduated college and I didn't have a job yet I was taking 150 mg of Zoloft. I had no health insurance and didn't have a docotor because I had always used the student health center for any of my health needs in college. I ended up stopping 150 mg of Zoloft cold turkey. Talk about brain zaps, high fevers, emotional swings, depression that lasted about 12 weeks. Not a pleasant experience. But after the 12 weeks things seemed to clear up and I was able to feel very good for a few years. But yes, withdrawal of these medications scares the crap out of me!

Thank you everyone for your posts...

If any other people want to post on here I think it would be helpful! There just isn't a lot of info about Depakote and PTSD out there (or on this site either). As time progresses I will post more about my own experiences with Depakote!
 
Depakote was the first medication I was put on at age 15 for PTSD, however I do recall a doc telling me later on that I needed to be on medication as long as I live due to my being bipolar. The bipolar thing was news to me.

Anyways I can't say Depakote helped anything, I'm sorry. Shortly after I was put on meds I started sleeping excessively and not caring about much including things that brought me joy. Since Depakote didn't work we moved on to another one, then another and another and on and on until after 12 years of this crap I finally said "Enough!
 
I have taken Depakote for years with no side effects, I no longer take it because other medication combo's are controlling my mood swings. I can't imagine how I would have felt if I hadn't taken it the years I did.

I currently take Seroquel, and the first time I took it, I felt like I had just woke up from a coma. My thoughts were clear, my memory was sharp, I had never felt so good. I take 200 mgs/nightly along with Prozac 60mg/daily, and the occasional Trazadone when I haven't slept in awhile. I try to stay away from it cause it causes a few days of groggy. When I first started Seroquel, it knocked me on my arse!! I now can take it and not feel sleepy at all. You have to build it up in your system.

I too, spent many years chasing proper diagnosis and treatment. I was labeled with many crazy illnesses. When I first starting trying to get help, it was the 80's. Not alot of good information or doctors then. For 12 years I went on and on. I finally found a good psychiatrist that was familiar with PTSD and bi-polar symptoms. I was told I was bi-polar, obsessive/compulsive, clinical depression, DID, PTSD. It wasn't until after I came here that I learned that it was ALL just PTSD. I don't care what you call it, just fix it please.
 
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