Another (ex) buckeye here. I also lived in Indy for about 18 months...but it's been a long time. If you're into eclectic shopping, eating, walking around - the Broad Ripple area is nice. There are (or used to be) a lot of interesting stores and outside dining. I also second the Children's Museum - even if you don't have kids, it's a pretty amazing place...and the zoo is very nice. Indy also has a vibrant downtown area that is relatively safe for a bigger city.